Science that is transforming lives and enabling the future

3 Questions to Ask When Choosing a Secondary Container for your Bulk Drug Substance

All Posts

3 Questions to Ask When Choosing a Secondary Container for your Bulk Drug Substance

Freezing down bulk drug substance (BDS) isn’t something you can play around with. This is a high value product where any failure or contamination due to the bag breaking can lead to delays in medicine getting to the patient. Making sure you pick the right solution to protecting that product makes a big difference.

Here are three questions you should be considering:

  1. How does this shell protect better than what I already have?
  2. Will this container maximize storage space in our freezer?
  3. How will this fit into my organization’s facility?

With large investments in drug development, a complex global supply chain and regulatory requirements, the journey to the patient is formidable. Next time you’re looking for a secondary BDS solution, ensure your manufacturer takes these factors into consideration:

Material Performance

  • Offering robust solutions that won’t comprise during a bag drop, throughout the freeze/thaw process and in transport that will meet performance demands.

Support and Flexibility

  • An applications engineering team, offering bespoke and off-the-shelf solutions to create end-to-end solutions committed to quick response times.


  • Having quick turnaround and availability for wide variety of offerings.


  • Looking at total value, how does the competition fare? Does the performance, support and supply compete?


  • Providing reliable BDS freeze/thaw solutions allowing customers the ability to scale their operations from initial R&D evaluation to large scale production.

Trusted Partner

  • Having total support providing robust and reliable single-use solutions for bulk drug freeze thaw backed by a robust supply chain.

We understand the implications of a faulty container for your single-use solution and continue to work on ways to protect the integrity of product throughout the biopharma process. Ensure your next partner does the same.

For more information about our secondary containers and single-use solutions,
visit our website: cold-chain bioprocessing.  

Related Posts

Billions of Particles, Countless Fibers, and Nine 9's

Here’s a challenge, say the number 9 out loud, nine times. 9, 9, 9, 9, 9, 9, 9, 9, 9.

Tiger Yield: The Importance of FOUP Maintenance

To wrap up the Year of the Tiger (2022), there are still lessons to be learned from the animal kingdom. A tiger out in the open roaming the savannah is at risk of injuries from predators, including human hunters. Wafers left out in the open in a fab are susceptible to damage that can cause dramatic yield drops. The larger the wafer diameter, the greater the risk.

From Penn State to Cold Storage Pioneer: Solving Life Sciences Problems Through a Pattern of Innovation

As the chief technologist for the Life Sciences Division at Trane Technologies, Scott Farrar knows a thing or two about ultra-low temperature control for the life sciences industry, perhaps drawing inspiration from his days at Penn State University enjoying peach ice cream. Scott’s biggest inspiration, however, was his entrepreneurial dad who started a solar equipment company, teaching Scott from a young age the importance of sciences, technology, engineering, and mathematics (STEM) education and solving problems. Scott carried those tools with him, and upon completing his formal education, went to work for a pharmaceutical manufacturing company in research and development, specializing in low-temp freezers and incubators as well as heat-momentum and mass-transfer-type processes for the pharmaceutical industry. His exposure to dilemmas and investigative approach is what drove him to create better customer experiences.